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STRUCTURAL AND CATALYTIC ROLES OF CYSTEINE RESIDUES IN HUMAN LYSYL-tRNA SYNTHETASE
(Georgetown University, 2014)
Aminoacyl-tRNA synthetases (AARS) are essential and ubiquitous enzymes responsible for attaching amino acids to their cognate tRNAs during protein biosynthesis in a process known as aminoacylation. Comparing the amino ...
EFFECTS OF TNFAIP8 KNOCKDOWN ON EGFR AND IGF-1R SIGNALING AND CYTOTOXICITIES OF TARGETED DRUGS IN NON-SMALL CELL LUNG CANCER CELLS
(Georgetown University, 2015)
Lung cancer is the most commonly diagnosed cancer and leading cause of cancer-related deaths worldwide. Non-small cell lung carcinoma (NSCLC) accounts for 85% of lung cancer cases. Molecular therapies targeting epidermal ...
North Korea's Transnational Media Commodity Network
(Georgetown University, 2015)
Why are there are increasing numbers of North Koreans inside the country willing to consume and share illegal foreign media over the last ten years, despite greater risk of capital punishment due to tighter border controls ...
The Alliance Dilemma: A Stronger Japan and Regional Stability
(Georgetown University, 2014)
This paper is an attempt to explain the United States's puzzling silence on Japan's potential development of autonomous strike capability. I argue that this is due to the U.S.'s fear of entrapment vis-à-vis Japan, which ...
Modeling State Decisions to Pursue Nuclear Weapons
(Georgetown University, 2014)
This paper addresses the puzzle of why states proliferate nuclear weapons, despite a widespread call for global nuclear disarmament and the high costs of non-compliance behavior that follow. Most existing research on the ...
Interactions of quinolinols, peptides and SNAP-25 with the protease domain of botulinum neurotoxin A
(Georgetown University, 2010)
Role of protein-protein interactions in protein import, cholesterol transport and steroid biosynthesis
(Georgetown University, 2010)
Iranian-Israeli relations : covert relations to open hostility
(Georgetown University, 2010)
Meeting the hybrid threat : the Israel defense force's innovations against hybrid enemies, 2000-2009
(Georgetown University, 2010)