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Experiments on Approaches to Named Entity Recognition in IsiZulu
(Georgetown University, 2021)
Named Entity Recognition (NER) has always been one significant part of Natural Language Processing technologies. This thesis investigates a range of approaches to address the NER task in isiZulu, a morphologically complex ...
Two-Generation Early Intervention Programs as Vehicles for Enhancing Parental Human Capital and Economic Self-Sufficiency
(Georgetown University, 2021)
Extant research on early intervention programs for economically disadvantaged families with very young children predominantly focuses on the benefits that accrue to the children. Yet, these “two-generation” interventions ...
Enhancing Anti-Cancer Properties of Human Natural Killer Cells
(Georgetown University, 2021)
Immunotherapy has revolutionized cancer treatment. Certain immunotherapies, such as immune checkpoint inhibitors and CAR-T cell therapy, provide long lasting remissions. Unfortunately, the majority of tumors are unresponsive ...
Ausencias y presencias de la nación: Una reconstrucción cultural de las identidades ibéricas
(Georgetown University, 2021)
This dissertation argues that the defeat of the Second Republic in the Civil War (1939) and the subsequent dictatorship (1939–1975) disrupted a nation-building process in Spain due to the hegemonic power of National ...
The Child's Gaze and the Politics of Memory and Mourning: Spatiality, Spectrality and Sound in Contemporary Spanish and Latin American Cinema
(Georgetown University, 2021)
Forgetting has become for many nations an undeniable part of their social and political reality, and in cases like Spain, has even been deemed the key to a future free from the repetition of conflict. However, the elimination ...
Improved Feature Localization Through Broadband Image Processing
(Georgetown University, 2021)
Traditional photographic digital images are acquired from an array of photodetector elements whose physical size and location define the image pixels. Each element measures the amount of light incident upon it. The images ...
The Effects of Diet Induced Obesity on Central Nervous System Function of APOE Mice
(Georgetown University, 2021)
APOE4 is the strongest genetic risk factor for Alzheimer’s Disease (AD) and obesity is one of the most common environmental risk factors for AD. With 25% of the population being APOE4 carriers and 40% of the population ...
Multimodal Evidence for Neurocognitive Alterations in Pediatric Obesity
(Georgetown University, 2021)
Pediatric obesity is increasing in prevalence and severity in the United States, with one in five adolescents meeting criteria for overweight (body mass index; BMI for age and sex >85th percentile) and one in three meeting ...
Defining the Factors that Regulate the Conversion to a Trailblazer Epithelial to Mesenchymal Transition State
(Georgetown University, 2021)
Tumor heterogeneity resulting from the co-existence of phenotypically diverse tumor cellpopulations is a major contributor in the pathogenesis of several human malignancies. In addition to the steady acquisition of heritable ...
Targeting WEE1 in Standard Therapy Resistant Estrogen Receptor Positive Breast Cancer
(Georgetown University, 2021)
Despite the success of antiestrogens in extending overall survival of patients with estrogen receptor positive (ER+) breast tumors, resistance to these therapies is prevalent. ER+ tumors that progress on antiestrogens are ...