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Cholinergic Modulation of GABAergic Inhibition Dynamics In The Striatum
(Georgetown University, 2014)
The striatum contains medium spiny neurons (MSNs) classified by their axonal projection and expression of dopamine receptors into D1+ and D2+ MSNs; and interneurons including choline acetyltransferase expressing interneurons ...
MMP-1 Overexpression Selectively Alters Inhibition in D1 Spiny Projection Neurons in the Nucleus Accumbens and Disrupts Amphetamine Induced Locomotion
(Georgetown University, 2018)
Protease activated receptor-1 (PAR-1) and its ligand, matrix metalloproteinase-1 (MMP-1), are altered in several neurodegenerative diseases. PAR-1 and MMP-1 signaling impact neuronal excitation and inhibition in various ...