Clinical Endpoints in Trials of Drugs for Cancer: Time for a Rethink?
BMJ: British Medical Journal 2002 June 8; 324(7350): 1389- 1391
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Registration of Drugs for Treating Cancer and HIV Infection: A Plea to Carry Out Phase 3 Trials Before Admission to the Market Koopmans, P.P. (1995-05-20)Drugs for cancer and HIV infection tend to be admitted to the market on the basis of results from phase 2 trials. Assessing the benefit-risk balance with phase 2 trials often is difficult -- the effect of the drug is usually ...