From Genomic Databases to Translation: A Call to Action
Knoppers, Bartha Maria
Harris, Jennifer R
Burton, Paul R
Hudson, Thomas J
Journal of medical ethics 2011 Aug; 37(8): 515-6
The rapid rise of international collaborative science has enabled access to genomic data. In this article, it is argued that to move beyond mapping genomic variation to understanding its role in complex disease aetiology and treatment will require extending data sharing for the purposes of clinical research translation and implementation.
Showing items related by title, author, creator and subject.
DataSHIELD: Resolving a Conflict in Contemporary Bioscience -- Performing a Pooled Analysis of Individual-Level Data Without Sharing the Data Wolfson, Michael; Wallace, Susan E; Masca, Nicholas; Rowe, Geoff; Sheehan, Nuala A; Ferretti, Vincent; LaFlamme, Philippe; Tobin, Martin D; Macleod, John; Little, Julian; Fortier, Isabel; Knoppers, Bartha M; Burton, Paul R (2010-10)Contemporary bioscience sometimes demands vast sample sizes and there is often then no choice but to synthesize data across several studies and to undertake an appropriate pooled analysis. This same need is also faced in ...