Developing a Placebo-Controlled Trial in Surgery: Issues of Design, Acceptability and Feasibility
Campbell, M K
Entwistle, V A
Cuthbertson, B H
Skea, Z C
Sutherland, A G
McDonald, A M
Norrie, J D
Carlson, R V
Trials 2011 February 21; 12: 50
Surgical placebos are controversial. This in-depth study explored the design, acceptability, and feasibility issues relevant to designing a surgical placebo-controlled trial for the evaluation of the clinical and cost effectiveness of arthroscopic lavage for the management of people with osteoarthritis of the knee in the UK.
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