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dc.creatorUbel, Peter Aen
dc.creatorSilbergleit, Roberten
dc.date.accessioned2016-01-09T00:35:15Zen
dc.date.available2016-01-09T00:35:15Zen
dc.date.created2011-02en
dc.date.issued2011-02en
dc.identifierdoi:10.1080/15265161.2010.540061en
dc.identifier.bibliographicCitationThe American journal of bioethics : AJOB 2011 Feb; 11(2): 1-8en
dc.identifier.urihttp://worldcatlibraries.org/registry/gateway?version=1.0&url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&atitle=Behavioral+equipoise:+a+way+to+resolve+ethical+stalemates+in+clinical+research.&title=The+American+journal+of+bioethics+:+AJOB+&volume=11&issue=2&date=2011-02&au=Ubel,+Peter+A;+Silbergleit,+Roberten
dc.identifier.urihttp://dx.doi.org/10.1080/15265161.2010.540061en
dc.identifier.urihttp://hdl.handle.net/10822/1018823en
dc.description.abstractRandomized trials depend on clinicians feeling that they are morally justified in allowing their patients to be randomized across treatment arms. Typically such justification rides on what has been called "clinical equipoise"--when there is disagreement of opinion among the community of experts about whether one treatment is better than another, then physicians can ethically enter their patients into a clinical trial, even if individual physicians are not at equipoise. Recent debates over prominent studies, however, illustrate that controversy can be easily created rather than dispelled by trials, with many clinicians choosing not to use the proven therapy until they receive more convincing evidence of its superiority. In such situations, we propose that a new standard of equipoise be used to guide decisions about the ethical justifications for research trials--a standard of behavioral equipoise. Under behavioral equipoise, a trial is potentially justifiable if it addresses behavioral resistance to prior scientific evidence.en
dc.formatArticleen
dc.languageenen
dc.sourceeweb:337259en
dc.subjectClinical Equipoiseen
dc.subjectClinical Researchen
dc.subjectPatientsen
dc.subjectPhysiciansen
dc.subjectResearchen
dc.subject.classificationQuality of Health Careen
dc.subject.classificationHuman Experimentation Policy Guidelines / Institutional Review Boardsen
dc.subject.classificationPhilosophy of Medicineen
dc.titleBehavioral Equipoise: A Way to Resolve Ethical Stalemates in Clinical Researchen
dc.provenanceCitation prepared by the Library and Information Services group of the Kennedy Institute of Ethics, Georgetown University for the ETHXWeb database.en
dc.provenanceCitation migrated from OpenText LiveLink Discovery Server database named EWEB hosted by the Bioethics Research Library to the DSpace collection EthxWeb hosted by DigitalGeorgetown.en


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