Electrodes in the Brain -- Ethical Criteria for Research and Treatment With Deep Brain Stimulation for Neuropsychiatric Disorders
Schlaepfer, Thomas E
Brain stimulation 2011 Jan; 4(1): 7-16
Deep brain stimulation (DBS) has been used for neuropsychiatric disorders in clinical and research settings for almost 50 years now. Recent evidence demonstrates some efficacy in treating obsessive-compulsive disorder and major depression in patients refractory to other treatment modalities beyond single case reports. This has led to a considerable surge of clinical and commercial interest in DBS for psychiatric indications. Because of the high vulnerability of psychiatric patients, the lack of extensive short- and long-term data about effectiveness and the rapid spread of questionable indications this new field in psychiatry requires ethical criteria that can be applied to both research and clinical decision-making.
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