Electrodes in the Brain -- Ethical Criteria for Research and Treatment With Deep Brain Stimulation for Neuropsychiatric Disorders
Schlaepfer, Thomas E
Brain stimulation 2011 Jan; 4(1): 7-16
Deep brain stimulation (DBS) has been used for neuropsychiatric disorders in clinical and research settings for almost 50 years now. Recent evidence demonstrates some efficacy in treating obsessive-compulsive disorder and major depression in patients refractory to other treatment modalities beyond single case reports. This has led to a considerable surge of clinical and commercial interest in DBS for psychiatric indications. Because of the high vulnerability of psychiatric patients, the lack of extensive short- and long-term data about effectiveness and the rapid spread of questionable indications this new field in psychiatry requires ethical criteria that can be applied to both research and clinical decision-making.
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Separating Hope From Hype: Some Ethical Implications of the Development of Deep Brain Stimulation in Psychiatric Research and Treatment Schlaepfer, Thomas E; Lisanby, S H; Pallanti, Stefano (2010-05)
Ethical Guidance for the Management of Conflicts of Interest for Researchers, Engineers and Clinicians Engaged in the Development of Therapeutic Deep Brain Stimulation Fins, Joseph J; Schlaepfer, Thomas E; Nuttin, Bart; Kubu, Cynthia S; Galert, Thorsten; Sturm, Volker; Merkel, Reinhard; Mayberg, Helen S (2011-06)The clinical promise of deep brain stimulation (DBS) for neuropsychiatric conditions is coupled with the potential for ethical conflicts of interest because the work is so heavily reliant upon collaborations between academia, ...