Financial Conflicts of Interest in Biomedical Research: The Need to Improve the System
Wang, Amy T
Montori, Victor M
Murad, Mohammad Hassan
Drug news & perspectives 2010 Nov; 23(9): 607-12
Fifty years ago, the issue of conflict of interest in biomedical research appeared in the national spotlight and has remained in a state of constant evolution. Government legislation caused a boom in collaborations between physicians, researchers, academic institutions and industry. These relationships continue to advance medical science and make meaningful progress, yet they may threaten the integrity of physicians and researchers and the public's trust in medicine. This article will highlight the evolution of industry relationships and conflict of interest over time, discuss methods by which industry can potentially exert effects and propose new directions for the future.
Showing items related by title, author, creator and subject.
Association Between Industry Affiliation and Position on Cardiovascular Risk With Rosiglitazone: Cross Sectional Systematic Review Wang, Amy T.; McCoy, Christopher P.; Murad, Mohammad Hassan; Montori, Victor M. (2010)OBJECTIVE: To explore a possible link between authors' financial conflicts of interest and their position on the association of rosiglitazone with increased risk of myocardial infarction in patients with diabetes. DATA ...
Stopping Randomized Trials Early for Benefit and Estimation of Treatment Effects: Systematic Review and Meta-Regression Analysis Bassler, Dirk; Briel, Matthias; Montori, Victor M; Lane, Melanie; Glasziou, Paul; Zhou, Qi; Heels-Ansdell, Diane; Walter, Stephen D.; Guyatt, Gordon H.; Flynn, David N.; Elamin, Mohamed B.; Murad, Mohammad Hassan; Abu Elnour, Nisrin O.; Lampropulos, Julianna F.; Sood, Amit; Mullan, Rebecca J.; Erwin, Patricia J.; Bankhead, Clare R.; Perera, Rafael; Ruiz Culebro, Carolina; You, John J.; Mulla, Sohail M.; Kaur, Jagdeep; Nerenberg, Kara A.; Schünemann, Holger; Cook, Deborah J.; Lutz, Kristina; Ribic, Christine M.; Vale, Noah; Malaga, German; Akl, Elie A.; Ferreira-Gonzalez, Ignacio; Alonso-Coello, Pablo; Urrutia, Gerard; Kunz, Regina; Bucher, Heiner C.; Nordmann, Alain J.; Raatz, Heike; da Silva, Suzana Alves; Tuche, Fabio; Strahm, Brigitte; Djulbegovic, Benjamin; Adhikari, Neill K.J.; Mills, Edward J.; Gwadry-Sridhar, Femida; Kirpalani, Haresh; Soares, Heloisa P.; Karanicolas, Paul J.; Burns, Karen E.A.; Vandvik, Per Olav; Coto-Yglesias, Fernando; Chrispim, Pedro Paulo M.; Ramsay, Tim (2010-03-24)CONTEXT: Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome that precipitated early stopping. ...
Wang, Yu-Li; Burridge, Keith; Dembo, Micah; Gabbiani, Giulio; Hanks, Steven K.; Hosoya, Hiroshi; Janmey, Paul; Karlsson, Roger; Lindberg, Uno; Mabuchi, Issei; Otey, Carol; Rottner, Klemens; Small, J. Victor; Wang, C.-L. Albert; Zigmond, Sally (2004-03-26)