Equipoise and Randomisation in Surgery
British Journal of Neurosurgery 2010 February; 24(1): 96-97; author reply 98-99
In science, when a prevailing model does not fit reality the model is changed to fit better. The process is often accompanied by noisy attempts from some quarters to change reality to fit the model. So it is with randomised trials in surgery, the letter of Helmy et al. being an example. The randomised model used in drug trials does not fit surgery well for several well-rehearsed reasons, a significant point of poor fit being the question of equipoise.
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