Aspectos fundamentais da experimentação animal - aplicações em cirurgia experimental
Damy, Sueli Blanes
Camargo, Roberto Souza
Figueiredo, Luiz Francisco Poli de
Revista da Associação Médica Brasileira (1992) 2010 Jan-Feb; 56(1): 103-11
This study aimed to present the general principles for experiments performed on laboratory animals as required by international and national ethical committees on animal welfare. Compliance to these principles is a prerequisite for publication in international journals. Details of genetic, sanitary and environmental standards, transportation, acclimation, environmental enrichment, appropriate education and training of all those involved in handling of live animals, information management strategy, biossecurity, diet, anesthesia, analgesia, postoperative care and euthanasia for Mus musculus (mice), Rattus norvegicus (rat), Oryctolagus cuniculus (rabbit) and Sus scropha domesticus (pig) combined with well planned biomedical research are fundamental to increase the accuracy, reproducibility and precision of the experimental results.
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