The Truth About Lying: Inhibition of the Anterior Prefrontal Cortex Improves Deceptive Behavior
Karim, Ahmed A
Cerebral cortex (New York, N.Y. : 1991) 2010 Jan; 20(1): 205-13
Recent neuroimaging studies have indicated a predominant role of the anterior prefrontal cortex (aPFC) in deception and moral cognition, yet the functional contribution of the aPFC to deceptive behavior remains unknown. We hypothesized that modulating the excitability of the aPFC by transcranial direct current stimulation (tDCS) could reveal its functional contribution in generating deceitful responses. Forty-four healthy volunteers participated in a thief role-play in which they were supposed to steal money and then to attend an interrogation with the Guilty Knowledge Test. During the interrogation, participants received cathodal, anodal, or sham tDCS. Remarkably, inhibition of the aPFC by cathodal tDCS did not lead to an impairment of deceptive behavior but rather to a significant improvement. This effect manifested in faster reaction times in telling lies, but not in telling the truth, a decrease in sympathetic skin-conductance response and feelings of guilt while deceiving the interrogator and a significantly higher lying quotient reflecting skillful lying. Increasing the excitability of the aPFC by anodal tDCS did not affect deceptive behavior, confirming the specificity of the stimulation polarity. These findings give causal support to recent correlative data obtained by functional magnetic resonance imaging studies indicating a pivotal role of the aPFC in deception.
Showing items related by title, author, creator and subject.
Investigating the Relationship between Long Chain Omega-3 Fatty Acids and Prefrontal Cortex Development during Adolescence Darcey, Valerie L. (Georgetown University, 2017)Delivery of building blocks essential for brain development is critical for the normal development of the brain and behavior. Omega-3 (N3) fatty acids are essential nutrients, which can only be obtained from the diet. ...
Egger, Matthias; Zellweger-Zahner, Tanja; Schneider, Martin; Junker, Christoph; Lengeler, Christian; Antes, Gerd (1997-08-02)