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Implementation and Enforcement of the 3Rs Principle in the Field of Transgenic Animals Used for Scientific Purposes. Report and Recommendations of the BfR Expert Workshop, May 18-20, 2009, Berlin, Germany Kretlow, Ariane; Butzke, Daniel; Goetz, Mario E; Grune, Barbara; Halder, Marlies; Henkler, Frank; Liebsch, Manfred; Nobiling, Rainer; Oelgeschlaeger, Michael; Reifenberg, Kurt; Schaefer, Bernd; Seiler, Andrea; Luch, Andreas (2010)In 2007, 2.7 million vertebrates were used for animal experiments and other scientific purposes in Germany alone. Since 1998 there has been an increase in the number of animals used for research purposes, which is partly ...