Bias in Treatment Assignment in Controlled Clinical Trials
Chalmers, Thomas C.
Smith, H. Jr.
New England Journal of Medicine 1983 December 1; 309(22): 1358-1361
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Chalmers, Thomas C.; Celano, Paul; Sacks, Henry S.; Smith, Harry (1983-12-01)The suggestion that bias in the assignment of patients to treatment or control groups may be an important determinant of the outcome of clinical trials was studied through a statistical analysis of 145 papers on controlled trials ...