Indifference of Subjects: An Alternative to Equipoise in Randomized Clinical Trials
Veatch, Robert M.
Social Philosophy and Policy 2002 Summer; 19(2): 295-323
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Binik, Ariella; Weijer, Charles; McRae, Andrew D; Grimshaw, Jeremy M; Boruch, Robert; Brehaut, Jamie C; Donner, Allan; Eccles, Martin P; Saginur, Raphael; Taljaard, Monica; Zwarenstein, Merrick (2011-05-11)This article is part of a series of papers examining ethical issues in cluster randomized trials (CRTs) in health research. In the introductory paper in this series, Weijer and colleagues set out six areas of inquiry that ...
Principles of Early Stopping of Randomized Trials for Efficacy: A Critique of Equipoise and an Alternative Nonexploitation Ethical Framework Buchanan, David; Miller, Franklin G. (2005-06)Recent controversial decisions to terminate several large clinical trials have called attention to the need for developing a sound ethical framework to determine when trials should be stopped in light of emerging efficacy ...