Graduate Theses and Dissertations - Global Infectious Disease Program
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The Identification of Transcriptional Signatures of Steroid Response in Human Neurons and Microrna Networks as a Contributor to Reproductive Steroid Pathology
(Georgetown University, 2021)Ovarian steroids change the brain in utero, during puberty, and in adulthood. At the neuronal level, ovarian steroids affect structure, gene networks, and physiological outputs, and at the neurocircuitry level they modulate ... -
Characterization and Analysis of Novel Antimalarial Drug Targets: Plasmodium falciparum Phosphatidylinositol Kinases
(Georgetown University, 2020)Artemisinin-based combination therapy (ACT) is the first-line treatment recommended for uncomplicated Plasmodium falciparum infections by the World Health Organization (WHO). ACTs are composed of an artemisinin (ART) drug ... -
Epidemiological inference and surveillance with high resolution medical claims data: the case of influenza
(Georgetown University, 2017)Disease surveillance, the activity of monitoring disease burden and its associated risk factors, is critical for situational awareness, disease control, and public health coordination and planning. Due to the opportunistic ... -
An Examination of Exposure and Risk Factors for Viral, Bacterial and Parasitic Diseases among Febrile Patients: A Surveillance Project in Kilombero, Tanzania
(Georgetown University, 2016)Introduction: The objective of this cross-sectional study was to employ quantitative and -
Integrating Epidemiological and Molecular Approaches to Study the Transmission and Treatment of Giardia lamblia
(Georgetown University, 2016)Giardia lamblia, a eukaryotic intestinal parasite, is one of the major causes of diarrheal disease, giardiasis, worldwide. The pathophysiological complications of Giardia infections include small intestinal barrier ...
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