This overview of ethics committees for biomedical and behavioral research considers principal issues in the role and operation of these committees in various countries. It suggests general guidelines derived from a ...

Relatively little has been written about the ethics of conducting early phase clinical trials involving subjects from the developing world. Below, I analyze ethical issues surrounding one of gene transfer's most widely ...

The randomization ingredient in double-blind controlled experiments may be objectionable to patients who, in their desperation, come to such trials seeking a last chance of cure. Minogue