Direct reprogramming and ethics in stem cell research
Byrnes, W. Malcolm
National Catholic Bioethics Quarterly 2008 Summer; 8(2): 277-290
The recent conversion of adult cells into so-called induced pluripotent stem (iPS) cells through direct reprogramming provides a historic opportunity to turn away from the ethically problematic use of embryonic stem cells isolated through the destruction of human embryos. Moreover, because iPS cells are patient specific, they render therapeutic cloning unnecessary. Nonetheless, iPS cells are tainted by their association with the human embryonic stem cell lines, derived in the past, which will be required for their validation. This concern is one that can be resolved.
Cell Lines; Cells; Cloning; Embryonic Stem Cells; Embryos; Ethics; Research; Stem Cells; Ips Cells; Reproduction / Reproductive Technologies; Cryobanking of Sperm, Ova, or Embryos; Genetics, Molecular Biology and Microbiology; Stem Cell Research; Artificial and Transplanted Organs or Tissues; Donation / Procurement of Organs and Tissues; Research on Special Populations; Research on Embryos and Fetuses;
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