PGD to reduce reproductive risk: the case of mitochondrial DNA disorders.
De Die-Smulders, C.E.M.
De Wert, G.
Human Reproduction 2008 November; 23(11): 2392-2401
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Nuclear transfer to prevent mitochondrial DNA disorders: revisiting the debate on reproductive cloning. Bredenoord, A L; Dondorp, W; Pennings, G; De Wert, G (2011-02)Preclinical experiments are currently performed to examine the feasibility of several types of nuclear transfer to prevent mitochondrial DNA (mtDNA) disorders. Whereas the two most promising types of nuclear transfer to ...
Avoiding transgenerational risks of mitochondrial DNA disorders: a morally acceptable reason for sex selection? Bredenoord, Annelien L; Dondorp, Wybo; Pennings, Guido; De Wert, Guido (2010-06)In this article, we discuss sex selection not intended to help a couple avoid having a child with a severe genetic disorder, but to avoid possible health risks further along the line of generations. Sex selection may be ...
Reproductive decision-making in the context of mitochondrial DNA disorders: views and experiences of professionals. Bredenoord, A.L.; Krumeich, A.; De Vries, M.C.; Dondorp, W.; De Wert, G. (2010-01)Although a scientific and ethical debate about the possible reproductive options for carriers of mitochondrial DNA (mtDNA) mutations is developing, not much information regarding the views and experiences of professionals ...