Ethicolegal aspects of cancer genetics.
Cancer treatment and research 2010; 155: 1-14
In the wake of efficacious preventive interventions based on hereditary cancer risk assessment, a number of ethical and legal challenges have emerged. These include issues such as appropriate testing of children and embryos, the "duty to warn" relatives about familial risk, reproductive genetic testing, the risk of genetic discrimination, and equitable access to testing. These and other issues will be discussed within the framework of a bioethical model, with reference to recent case law.
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Offit, Kenneth; Gilewski, Teresa; McGuire, Peter; Schluger, Alice; Hampel, Heather; Brown, Karen; Swensen, Jeff; Neuhausen, Susan; Skolnick, Mark; Norton, Larry; Goldgar, David (1996-06-15)
Ethical and Legal Implications of Cancer Genetic Testing: Do Physicians Have a Duty to Warn Patients' Relatives About Possible Genetic Risks? Storm, Courtney; Agarwal, Rinki; Offit, Kenneth (2008-09)This vignette raises questions about the extent of physicians' obligations to warn relatives of a patient about a hereditary cancer risk.