Resolving ethical issues in stem cell clinical trials: the example of Parkinson disease.
The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2010 Summer; 38(2): 257-66
Clinical trials of stem cell transplantation raise ethical issues that are intertwined with scientific and design issues, including choice of control group and intervention, background interventions, endpoints, and selection of subjects. We recommend that the review and IRB oversight of stem cell clinical trials should be strengthened. Scientific and ethics review should be integrated in order to better assess risks and potential benefits. Informed consent should be enhanced by assuring that participants comprehend key aspects of the trial. For the trial to yield generalizable knowledge, negative findings and serious adverse events must be reported.
Permanent LinkFind Full Text at Georgetown University Library
Full Text from Publisher
Showing items related by title, author, creator and subject.
Benefits, risks and ethical considerations in translation of stem cell research to clinical applications in Parkinson?s disease Master, Zubin; McLeod, Marcus; Mendez, Ivar (2007-03)Stem cells are likely to be used as an alternate source of biological material for neural transplantation to treat Parkinson's disease in the not too distant future. Among the several ethical criteria that must be fulfilled ...