A monoclonal mouse? One potential use of nuclear-transplantation -- cloning -- technology is to generate genetically matched tissues for treating adult patients. But there's a debate about whether mature adult cells are a good source of nuclei.
Nature 2002 February 28; 415(6875): 967, 969
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The other stem-cell debate: To test the potential curative powers of human embryonic stem cells, biologists want to inject them into lab animals. Creating such chimeras makes perfect sense, to a point: a sheep with a human liver? O.K. A mouse brain made up of human cells? Maybe. But a chimp that sobs? Shreeve, Jamie (2005-04-10)