Search Full Text
Now showing items 1-10 of 17
Identification of A-to-I RNA Editing Sites in the Honey Bee (Apis mellifera) Brain Using RNAseq Data
(Georgetown University, 2014)
RNA editing is a post-transcriptional modification process that leads to addition, substitution and deletion of certain bases in RNA molecules, and accordingly alters their biological properties. As the most widespread ...
Giardia lamblia, the Intestinal Microbiome, and Innate Immunity: A Study of the Host-Parasite Relationship during G. lamblia Infection
(Georgetown University, 2015)
Infection with the protozoan parasite G. lamblia is a major cause of diarrheal disease worldwide. Prevalence is highest in developing countries with an estimated 20-30% of the population infected at any given time. G. ...
Characterization of the Function of Sox21 During Neurogenesis
(Georgetown University, 2014)
Neurogenesis, the progression from neural progenitor to committed neuron, is a tightly regulated process that is fundamental for development of the central nervous system. Whereas the SoxB1 transcriptional activators are ...
FITNESS, POLLEN DISPERSAL, AND FLORAL-DISPLAY SIZE EVOLUTION IN ANIMAL-POLLINATED PLANTS
(Georgetown University, 2011)
The great variation in floral-display size (the number of flowers per plant) (FDS) in the thousands of angiosperm species has intrigued biologists and others for centuries, eliciting investigations regarding the ecology, ...
Age Determination, Life History and Juvenile Behavior in Bottlenose Dolphins (Tursiops sp.) in Shark Bay, Australia
(Georgetown University, 2013)
Although of theoretical interest, the juvenile period in mammals is a relatively neglected area of research. In large-brained and social mammals, such as bottlenose dolphins, where juvenile periods are prolonged, life ...
Computational Analysis of Difficult-to-predict Genes and Detection of Lineage-specific Genes in Honey Bee (Apis mellifera)
(Georgetown University, 2013)
Honey bees are key agricultural pollinators and a research model for social behavior and the evolution of eusociality. Generation of reliable gene predictions is critical to the success of laboratory experiments and ...
THE ROLES OF TWO SMALL GTP-BINDING PROTEINS ARL1 AND YPT6 IN AUTOPHAGY
(Georgetown University, 2016)
Autophagy is a cellular degradation process that sequesters organelles or proteins into a double-membraned structure called the phagophore; this transient compartment matures into an autophagosome, which then fuses with ...
SIW14 IS A NOVEL 5-DIPHOSPHOINOSITOL PENTAKISPHOSPHATE (5PP-IP5) PHOSPHATASE THAT NEGATIVELY REGULATES THE STRESS RESPONSE
(Georgetown University, 2016)
Inositol pyrophosphates are high energy signaling molecules involved in cellular processes such as energetic metabolism, telomere maintenance, vesicle trafficking, and the stress response. While the inositol kinases ...
Learning, brain plasticity, and foraging behavior in hemimetabolous insects
(Georgetown University, 2011)
Foraging is an essential component of an animal's fitness, and learning plays an important role in foraging for many animals. A deeper understanding of complex behaviors such as foraging and learning requires an interdisciplinary ...
LESS IS MORE: THE IMPLICATIONS OF GENOMIC MINIMALISM ON THE REGULATION OF GENE EXPRESSION IN THE PARASITE GIARDIA LAMBLIA
(Georgetown University, 2012)
<italic>Giardia lamblia<italic> is one of the most common eukaryotic intestinal parasites in the world. A theme of simplified cellular machinery characterizes much of its biology with interesting consequences: a greatly ...