Browsing Graduate Theses and Dissertations - Chemistry by Title
Now showing items 24-43 of 152
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Capsules and cavitands : concave molecules built on the cyclotribenzylene (CTB) scaffold
(Georgetown University, 2011) -
Catalytic C-C Bond Construction Using Fluorine and Chlorine-Containing Nucleophiles
(Georgetown University, 2019)The high synthesis demand from upstream industries requires the development of new methods that produce fluorine and chlorine-containing compounds. To this end, a catalytic strategy was developed to achieve the insertion ... -
Chalcogenide-Stabilized Metal Nanoclusters: Synthesis, Characterizations, and Applications
(Georgetown University, 2022)This dissertation focuses on the atomically precise gold NPs, or NCs. Au25(SR)18 is selected as the model to investigate the magnetic properties of this NC in Chapter III. Pentanethiol, hexanethiol and octanethiol are used ... -
Characterization of Multimethylation in Ricksettsia Outer Membrane Protein B (OMPB) Catalyzed by Lysine Methyl Transferases
(Georgetown University, 2014)Rickettsiae are causative agents of typhus and spotted fever. Early detection and vaccines are crucially needed. The observation of correlation between methylation of lysine residues in rickettsial outer membrane protein ... -
Circular Dichroism Sensing of Chiral Compounds with a Meso (Salen)Cobalt Complex
(Georgetown University, 2014)Coordination of a chiral substrate to (meso-salen)cobalt(II) nitrate and subsequent oxidation generates a Co(III) complex exhibiting a strong chiroptical readout that is attributed to spontaneous substrate-to-ligand chirality ... -
Complexation of Air Gases in Small Cryptophanes
(Georgetown University, 2018)The molecule-within-molecule complexes of the container molecules constitute a fascinating branch of supramolecular chemistry that has broad-reaching implications. Since 1981, cryptophanes, defined by the connection of two ... -
Computational studies of electron transfer proteins : Rubredoxin-type proteins and ferredoxin
(Georgetown University, 2011) -
Continuum electrostatics calculations of reduction potentials of rubredoxins
(Georgetown University, 2010) -
Copper and Zinc Catalyzed Additions of Alkynes and Ynamides to Carbonyl Electrophiles
(Georgetown University, 2017)Fluorine-containing pharmaceuticals are of increasing interest which is at least partly due to the favorable stability to biodegradation, increasing bioavailability and lipophilicity and other desirable pharmacological and ... -
Copper Catalyzed C-C Bond Formation with Ynamides and Fluorinated Enolates
(Georgetown University, 2014)The addition of ynamides to N-heterocycles activated in situ with ethyl chloroformate has been accomplished at room temperature using copper iodide as catalyst. The addition to pyridines and quinolines proceeds with good ... -
Crystal growth of polymorphic bis-diphenyl ureas on self-assembled monolayer templates
(Georgetown University, 2009) -
Crystalline Organic Cavitands as Microcavity Materials
(Georgetown University, 2015)There has been much interest in inefficiently packed molecular materials and their applications in gas storage, separations, catalysis, etc. Such known materials include metal-organic frameworks (MOFs), polymers of intrinsic ... -
Crystallization and phase transformation of uric acids
(Georgetown University, 2010) -
Dehydration and Dopant Effects in Nucleic Acid Hydrates
(Georgetown University, 2017)The dehydration mechanism and the inclusion of molecular dyes (dopants) in two nucleic acid hydrates, thymine and cytosine, were investigated. Thymine hydrate (TH) was identified as a modulated system which undergoes a ... -
Design and Synthesis of Aryl Amphiphiles to Control the Growth of π-Conjugated Microcrystals along the π-Stack Direction
(Georgetown University, 2021)Photonic integrated circuits (PICs) are capable of overcoming the numerous limitations facing traditional integrated circuits, such as the heat generated by the fast movement of electrons and the size limitations. However, ... -
Design, Synthesis, and Applications of Stereodynamic Chirality Probes
(Georgetown University, 2015)Novel stereodynamic chirality probes were developed for enantioselective sensing of chiral compounds, utilizing the concepts of dynamic covalent chemistry and metal-ligand coordination. Upon interaction with a chiral ... -
Design, Synthesis, and High-throughput Applications of Small Molecule Chiroptical Probes
(Georgetown University, 2020)This work showcases several chirality sensors that undergo covalent bond formation with small amine-containing molecules and thus produce a circular dichroism (CD) signal that can be used for chiroptical analysis of the ... -
DEVELOPMENT AND CHARACTERIZATION OF CONDUCTING POLYMER MODIFIED ELECTRODES FOR NEUROLOGICAL APPLICATIONS
(Georgetown University, 2011)Electrodes have the potential to be applied to neurological signal detection, neurotransmitter detection, or neurological stimulation, but there are many factors to consider. These factors include the electrochemical ... -
Development of Enantioselective Agents and Heme-Targeted Antimalarials
(Georgetown University, 2011)Several chiral 3,5-dinitrobenzoyl-derived amides were prepared and applied in enantioselective NMR analysis of protected amines. It was found that (R)-N-(1-(naphthalen-1-yl)ethyl)-3,5-dinitrobenzamide is a very effective ...
