Browsing Graduate Theses and Dissertations - Chemistry by Title
Now showing items 73-92 of 147
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Lewis acid assisted metal-ligand bifunctional hydrogenation of amides
(Georgetown University, 2009) -
Luminescent Bismuth(III)-Organic Compounds: Synthesis and Spectroscopic Properties
(Georgetown University, 2019)This work focuses on the synthesis and characterization of bismuth(III)-organic compounds with an eye towards developing structure-photoluminescent behavior relationships in bismuth-based materials. Twenty-eight compounds ... -
Macrosolute effects on nucleic acids
(Georgetown University, 2008) -
Magnetic and thermal studies of doped rare-earth chalcogenide nanostructures in solution and the solid-state
(Georgetown University, 2012)The europium chalcogenides (oxide, sulfide, selenide) are intrinsically ferromagnetic semiconductors. Research with these types of materials is motivated by applications in fields such as spintronics, which can take advantage ... -
MAGNETIC MESOPOROUS SILICA NANOPARTICLES AS POTENTIAL MRI CONTRAST AGENTS
(Georgetown University, 2016)Magnetic resonance imaging is a non-invasive diagnostic technique that utilizes native protons in biological samples to produce three-dimensional images. MR imaging relies on the native differences in relaxation time (T1 ... -
Mechanical Properties and Heterogeneous Growth of Uric Acid Crystals
(Georgetown University, 2019)The mechanical and structural properties of the anhydrous (UA) and the dihydrate (UAD) forms of uric acid crystals were investigated. UA, the more stable form, was found to have a substantially higher Young’s modulus and ... -
Mechanisms of SNAP-25 Association with Botulinum Neurotoxin Light Chain A and SNARE Proteins
(Georgetown University, 2012)Botulism neurotoxins (BoNTs), a family of neurotoxins produced by the anaerobic bacterium Clostridium botulinum, are the most poisonous biological toxins known to man and are listed as category A bioterrorism agents by the ... -
Mechanistic insight into the Brust-Schiffrin two-phase method for organochalcogenate-protected metal nanoparticles
(Georgetown University, 2011) -
Mechanistic Insights into Catalytic Bond Formation and Electrocatalytic Ammonia Oxidation
(Georgetown University, 2021)Computational chemistry is a useful technique to gain insight into reaction mechanisms when utilized in combination with synthesis and experimental characterization. Organometallic chemistry particularly benefits from a ... -
Mechanistic Insights into Copper Catalyzed sp3 C-H Functionalization
(Georgetown University, 2015)Direct C-H functionalization offers opportunities to modify carbon centers normally inert to traditional methods that rely on functional group manipulations, diversifying methods for complex organic molecule synthesis. ... -
Mechanistic Insights of Reactions Catalyzed by OmpB Lysine Methyltransferases
(Georgetown University, 2018)Protein lysine methylation of rickettsial OmpB (outer membrane protein B) has been implicated in the virulence of the typhus group of Rickettsia. N- and O-methylations have also been observed in virulence-relevant outer ... -
Mechanistic Studies of Copper and Iron Catalyzed Ammonia Oxidation
(Georgetown University, 2021)Global energy demand is increasing because of industrialization and population growth. Fossil fuels (oil, natural gas, and coal) provide about 88% of the energy needed to meet current demand. The two major problems associated ... -
Mechanistic Studies of Copper and Nickel Catalyzed sp3 C−H Functionalization
(Georgetown University, 2019)sp3 C−H functionalization represents a paradigm shift from the conventional rationality of organic synthesis. Classical organic synthesis relies on the manipulation of functional groups while the new logic of C−H ... -
Mechanistic Studies of Enhancing Performance of Pt-Based Electrocatalysts for Oxygen Reduction Reaction and Formic Acid Oxidation Reaction by Surface Modifications
(Georgetown University, 2018)Proton exchange membrane fuel cell (PEMFC) has been a topic of great interest due to its importance in energy conversion. Currently, the insufficient activity and high cost of electrocatalysts are the main reasons that ... -
Metal and Non-Metal Catalyzed Beta-Alkylation of Secondary Alcohols: Scope and Mechanism
(Georgetown University, 2014)Hydrogen Borrowing has emerged as an advantageous synthetic methodology due to its green chemistry nature. The concept of in–situ temporary alcohol oxidation followed by functionalization and reduction has been ... -
Metal and Non-Metal Catalyzed Transfer Hydrogenation and On-Water Reactivity
(Georgetown University, 2014)Three projects were explored for this dissertation 1) Metal Catalyzed Transfer Hydrogenation, 2) Non-Metal Catalyzed Transfer Hydrogenation and 3) On-Water Reactivity. For the first project, Noyori's Ru catalyst1, which ... -
METAL ION-MEDIATED INACTIVATION AND SMALL MOLECULE INHIBITION OF THE METALLOPROTEASE IN BOTULINUM NEUROTOXIN A
(Georgetown University, 2013)Botulinum neurotoxins are the causative agents of botulism and serotype A (BoNT/A) is the most persistent one among seven Clostridium botulinum serotypes. Current treatments for BoNT/A toxicity do not meet the demand of a ... -
Metal-Oxo Containing Polymer Nanobeads As Potential Contrast Agents for Magnetic Resonance Imaging
(Georgetown University, 2011)Magnetic resonance imaging (MRI) has greatly revolutionized the way diseases are detected and treated, as it is a non-invasive imaging modality solely based on the interaction of radiowaves and hydrogen nuclei in the ... -
Metal-Oxo Polymer Nanobeads as Potential Multi-Modal Contrast Agents for Magnetic Resonance Imaging
(Georgetown University, 2018)Magnetic Resonance Imaging (MRI) has become one of the most powerful non-invasive imaging modalities in clinical diagnostics and research, being able to distinguish soft tissues at a very high spatial resolution. The use ... -
Modeling Bioinorganic Nitric Oxide Signaling Chemistry
(Georgetown University, 2019)Nitrite (NO2-) is an important reservoir of nitric oxide (NO), which participates in a wide range of physiological activities such as neurotransmission, vasodilation, and immune response. Nitrite represents a tightly ...
