Browsing Graduate Theses and Dissertations - Chemistry by Creation Date
Now showing items 1-20 of 167
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Molecules and assemblies constructed from calix[4]resorcinarenes and their derivatives, syntheses and study
(Georgetown University, 2008) -
Macrosolute effects on nucleic acids
(Georgetown University, 2008) -
Palladium-phosphinous acid-catalyzed carbon-carbon and carbon-heteroatom bond formation and synthesis of new antimalarial drugs
(Georgetown University, 2008) -
The synthesis of precursors towards a Pin1-activatable Gd(III) MRI contrast agent
(Georgetown University, 2008) -
NEW INSIGHTS INTO THE ROLES OF METALS IN NITRIC OXIDE DELIVERY
(Georgetown University, 2009)The biochemistry of organic nitroso compounds (E-NO, E = RS, RO, R2N, R) is connected to that of nitric oxide. These organic derivatives can serve either as sources of NO in vivo or produce similar effects as NO such as ... -
Biochemical and biophysical analysis of recombinant Plasmodium falciparum chloroquine resistance transporter (pfcrt)
(Georgetown University, 2009) -
REACTIVITY OF NITRIC OXIDE AND S-NITROSOTHIOLS WITH LOW-COORDINATE ZINC AND NICKEL CENTERS
(Georgetown University, 2009)Nitric oxide (NO) and biologically relevant sources of NO such as S-nitrosothiols (RSNOs) have become a topic of great interest due to their regulation of biological functions including vasorelaxation, neurotransmission, ... -
Crystal growth of polymorphic bis-diphenyl ureas on self-assembled monolayer templates
(Georgetown University, 2009) -
Tuning the activity of platinum electrocatalysts via size, shape and capping polymer
(Georgetown University, 2009) -
Analysis of the cellular and molecular mechanisms of Chloroquine Resistance in Plasmodium Falciparum
(Georgetown University, 2009) -
ASYMMETRIC CATALYSIS AND SENSING WITH RIGID C2-SYMMETRIC LIGANDS AND DEVELOPMENT OF HEME-TARGETED ANTIMALARIALS
(Georgetown University, 2009)The first general procedure for the ligand-catalyzed nucleophilic addition of diethylzinc to trifluoromethyl ketones was developed. A range of 2-aryl-1,1,1-trifluorobutan-2-ols have been prepared in up to 99% yield using ... -
Electrochemical Studies and In Situ Electrochemical Nuclear Magnetic Resonance Investigations on Platinum-based Bimetallic Electrocatalysts for Direct Methanol Fuel Cells
(Georgetown University, 2009)Two parallel objectives of this thesis research are 1) to investigate the electrocatalytic activities of Pt-based bimetallic nanoparticles (NPs) towards methanol (MeOH) electro-oxidation reaction (MOR), carbon monoxide ... -
Exploiting Structural Disorder to Enhance Small Molecule Inhibition of the Oncoprotein c-Myc DImerization with its Partner Max
(Georgetown University, 2009)The transcription factor c-Myc, in its normal function, is involved in cell cycle regulation. The uncontrolled cell proliferation consequent to c-Myc deregulation is typical of cancer and neoplastic diseases. Most known ... -
Lewis acid assisted metal-ligand bifunctional hydrogenation of amides
(Georgetown University, 2009) -
SMALL MOLECULE BINDING OF INTRINSICALY DISORDERED PROTEINS: MULTIPLE BINDERS ON MULTIPLE SITES
(Georgetown University, 2009)Intrinsically disordered (ID) proteins lack a stable tertiary structure and exist in an ensemble of rapidly inter-converting conformations. They are prevalent in human and other genomes, and are biologically active in ... -
Interactions of quinolinols, peptides and SNAP-25 with the protease domain of botulinum neurotoxin A
(Georgetown University, 2010) -
INVESTIGATION OF FREQUENCY-INDEPENDENT IMPEDANCE BEHAVIOR IN CONDUCTING POLYMERS
(Georgetown University, 2010)Biocompatibility and low, frequency-independent impedance are critical in the design of electrodes for bioelectric signal sensing applications. These conditions could be regarded as the minimum requirements in order to ... -
New insights on the structure-function principles and design of quinoline antimalarial drugs
(Georgetown University, 2010) -
Beta-diketiminato copper complexes in C-H bond amination
(Georgetown University, 2010)
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