Graduate Theses and Dissertations - Neuroscience: Recent submissions
Now showing items 1-5 of 112
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Investigation of the Role of the p75 Neurotrophin Receptor in HIV-1 gp120-associated Synaptic and Neural Injury
(Georgetown University, 2022)Human immunodeficiency virus type 1 (HIV) remains a tenacious global pandemic nearly 40 years after its initial description in humans, currently affecting greater than 37 million individuals worldwide. Despite significant ... -
Neural Circuits of Sensorimotor Gating and Social Behavior in Nonhuman Primates
(Georgetown University, 2022)The nucleus accumbens (NAc) is a critical limbic-motor interface that is important for both processing reward and generating voluntary and reflexive motor outcomes. The NAc receives dense dopaminergic input from the ventral ... -
Language System Plasticity in Healthy Development and After Perinatal Stroke
(Georgetown University, 2022)Language processing is an extremely important, uniquely human cognitive ability. For well over a century, researchers have sought to understand how the human brain implements a system for instantaneously recognizing and ... -
The Effects of Traumatic Brain Injury on Sleep and Circadian Rhythms
(Georgetown University, 2022)Sleep and circadian rhythm disruptions are prevalent in neurodegenerative diseases, and exacerbate impairments in cognitive function, emotional and physical health. Traumatic brain injury (TBI) is a significant risk factor ... -
Creatine Synthesis and Supplementation Regulates Central Nervous System Postnatal Development and Injury
(Georgetown University, 2021)Cerebral creatine deficiency syndrome (CCDS) is an inborn error of metabolism characterized by intellectual delays, seizures, and autistic-like behavior. Exactly how endogenously synthesized creatine regulates central ...
