Graduate Theses and Dissertations - Biochemistry and Molecular & Cellular Biology
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Investigating the Impact of Pancreatic Cancer Derived Extracellular Vesicles on the Tumor Microenvironment
(Georgetown University, 2022)Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5-year survival rate of ~11%. Late-stage diagnosis of disease is a key driver of poor outcomes. To improve patient survival, a better understanding of early ... -
Associations between Polymorphisms in Genes in the Nitrite Synthesis Pathway and Mammographic Breast Density, a Biomarker of Breast
(Georgetown University, 2021)The nitrite synthesis pathway may play a role in breast cancer by activating the estrogen receptor alpha (ERα) through an interaction with the ligand-binding domain of the receptor in the absence of estradiol. ERα plays a ... -
The Exploration of Non-Invasive Biomarkers for Lupus Nephritis
(Georgetown University, 2021)Background -
Associations between Polymorphisms in Genes in the Nitrite Synthesis Pathway and Mammographic Breast Density, a Biomarker of Breast
(Georgetown University, 2021)The nitrite synthesis pathway may play a role in breast cancer by activating the estrogen receptor alpha (ERα) through an interaction with the ligand-binding domain of the receptor in the absence of estradiol. ERα plays a ... -
The Exploration of Non-Invasive Biomarkers for Lupus Nephritis
(Georgetown University, 2021)Background
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