Browsing Graduate Theses and Dissertations - Biochemistry and Molecular & Cellular Biology by Creator "Banerjee, Partha P"
Now showing items 1-3 of 3
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Investigating the Impact of Pancreatic Cancer Derived Extracellular Vesicles on the Tumor Microenvironment
(Georgetown University, 2022)Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5-year survival rate of ~11%. Late-stage diagnosis of disease is a key driver of poor outcomes. To improve patient survival, a better understanding of early ... -
Mahanine Disrupts Androgen Receptor Signaling in Human Prostate Cancer Cells
(Georgetown University, 2014)Continued reliance on androgen receptor (AR) signaling is an established hallmark of prostate cancer and castration-resistant prostate cancer (CRPC). Recent findings implicate the androgen receptor splice variant, ARv7 in ... -
PBK promotes aggressive behavior of prostate cancer cells through upregulation of a β-catenin/TCF/LEF- and MYC-driven pro-metastasis gene expression program
(Georgetown University, 2016)A key question in prostate cancer research is how to distinguish aggressive prostate cancer from indolent neoplasms. Early treatment of aggressive cancers is essential to maximize therapeutic potential but treatment carries ...
