• The Contribution of PCPH to Colon Carcinoma 

      MacCarthy, Caitlin Marie (Georgetown University, 2011)
      PCPH is a well conserved, single-copy gene whose product is ubiquitously expressed but predominates in kidney, liver, and colon. The protein product belongs to the nucleoside triphosphate diphosphohydrolase family, NTPDase, ...
    • p15Ink4b Loss Impairs the Maturation and Activation of Conventional Dendritic Cells 

      Fares, Joanna (Georgetown University, 2012)
      p15Ink4b, an inhibitor of cyclin-dependent kinases, is a tumor suppressor frequently associated with hematological malignancies. Its inactivation through DNA methylation is one of the most prevalent epigenetic alterations ...