Beta-diketiminato nickel and copper complexes in C-N bond formation and N-O bond activation
Thesis (Ph.D.)--Georgetown University, 2011.; Includes bibliographical references.; Text (Electronic thesis) in PDF format. Carbon-nitrogen bond formation (C-N) is an essential process in synthetic chemistry. The ability to form C-N bonds without traditional functional group manipulations can decrease synthetic steps and chemical byproducts.; A focus of this work is the development of nickel and copper systems for catalytic C-N bond formation. Our approach involves the discovery of stoichiometric transformations, study of mechanistic details, and application of these insights to develop new catalytic protocols for C-N bond formation.
Showing items related by title, author, creator and subject.
Aguila, Mae Joanne Budol (Georgetown University, 2014)C-H amination is an attractive methodology for constructing C-N bonds from seemingly unreactive C-H bonds. This process reduces group manipulations and reaction by-products. C-H amination catalysts are usually rhodium and ...
Pharmacological Properties of alpha4beta2 and alpha3beta4 Nicotine Acetylcholine Receptors: Ligand Binding, Activation, Desensitization, and Interspecies Differences Tuan, Edward (Georgetown University, 2014)Smoking cessation medications using nicotinic ligands, including nicotine, cytisine, and varenicline, have traditionally revolved around selective activation of alpha4beta2 nicotinic acetylcholine receptors (nAChRs). ...