Identification, pharmacology and anatomical localization of heteromeric neuronal nicotinic acetylcholine receptors in the rat hippocampus : effects of nicotine on nicotinic receptors expressed in rat primary cultured neurons
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DeDominicis, Kristen Elizabeth (Georgetown University, 2015)Nicotinic acetylcholine receptors (nAChRs) are present throughout the nervous system where they mediate and modulate neurotransmission. The α4β2* subtype is the most prevalent high affinity nAChR expressed in the brain. ...
Pharmacological Properties of alpha4beta2 and alpha3beta4 Nicotine Acetylcholine Receptors: Ligand Binding, Activation, Desensitization, and Interspecies Differences Tuan, Edward (Georgetown University, 2014)Smoking cessation medications using nicotinic ligands, including nicotine, cytisine, and varenicline, have traditionally revolved around selective activation of alpha4beta2 nicotinic acetylcholine receptors (nAChRs). ...
Glass, Kathleen Cranley; Weijer, Charles; Palmour, Roberta M.; Shapiro, Stanley H.; Lemmens, Trudo M.; Lebacqz, Karen (1996-07)