Georgetown University Medical Center
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The Coalition for Epidemic Preparedness Innovations (CEPI) and the Partnerships of Equitable Vaccine Access
(Cambridge University Press, No Date)This article highlights and evaluates the role of CEPI and its contribution to global equitable access to COVID-19 vaccines through its established partnerships for vaccine development. The article adds to the understanding ... -
Spoken Language Processing Activates the Primary Visual Cortex
(PLoS ONE, 2023-02-17)Abstract Primary visual cortex (V1) is generally thought of as a low-level sensory area that primarily processes basic visual features. Although there is evidence for multisensory effects on its activity, these are ... -
Delayed treatment with ceftriaxone reverses the enhanced sensitivity of TBI mice to chemically-induced seizures
(PLOS One, 2022-12-08)The pathophysiological changes that occur after traumatic brain injury (TBI) can lead to the development of post-traumatic epilepsy, a life-long complication of brain trauma. The etiology of post-traumatic epilepsy remains ... -
Modulation of Synaptic Plasticity by Phosphorylation of Amyloid Precursor Protein at Distinct Residues
(Georgetown University, 2023)Alzheimer's Disease (AD), the most common neurodegenerative disorder, is characterized by progressive cognitive impairment. Histopathological hallmarks include Aβ accumulation and tau phosphorylation. Aβ formation starts ... -
Deficiency in CCR5, a Mediator of Neuroinflammation, Normalizes TIMP Levels, Working Memory, and Gamma Oscillation Power in APOE4 Targeted Replacement Mice
(Georgetown University, 2023)The APOE4 allele increases the risk for Alzheimer’s disease (AD) in a dose-dependent manner and is also associated with cognitive decline in non-demented elderly controls. In mice with targeted gene replacement (TR) of ...