Browsing Georgetown University Medical Center by Title
Now showing items 177-196 of 505
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Generalization and maintenance in aphasia rehabilitation
(Georgetown University, 2010) -
Genetic Influences of Dopamine and GABA on Adolescent Cognition
(Georgetown University, 2018)Adolescence is a time of exploration, but also risk taking, such as alcohol use. What places individuals’ at risk has not been fully elucidated. Twin studies of adult alcohol use disorders (AUD’s) found genetics account ... -
Genetic regulation of the generation of neuronal diversity in the developing mammalian basal forebrain
(Georgetown University, 2010) -
A GENOME-SCALE CRISPR SCREEN TO IDENTIFY ESSENTIAL GENES FOR THE EFFECTOR FUNCTION OF CYTOTOXIC T LYMPHOCYTES
(Georgetown University, 2017)Somatic gene mutations and dysregulations can alter the vulnerability of a cancer cell to T cell based immune selection. To systematically identify genes that positively regulate the sensitivity of cancer cells to T ... -
Health Maintenance Education for Caregivers of Pediatric Inflammatory Bowel Disease Patients: Impact on Knowledge and Adherence
(Georgetown University, 2021)Pediatric Inflammatory Bowel Disease (IBD) has the potential to affect growth, pubertal and psychosocial development. Limited knowledge and adherence can be problematic for both children with IBD and their caregivers. ... -
Health Systems Innovating to Address Food Insecurity: Analysis of Program Implementation, Evaluation, and the Future
(Georgetown University, 2020)While individuals have always been able to recognize the influence of social factors on their health, and ability to attain healthcare, the healthcare industry has only recently shifted their attentiveness to the impacts ... -
HEMATOPOIETIC CELL POPULATION SEGREGATION THROUGH FULL-LENGTH TRANSCRIPTOME SEQUENCING
(Georgetown University, 2015)“Progress in science results from new technologies, new discoveries and new ideas, probably in that order.” Nobel Laureate Sydney Brenner (1927 - ) -
Heterogeneity of interneuron circuit function in sensory processing and synaptic plasticity
(Georgetown University, 2011) -
Hijacking the Candida albicans Multidrug Resistant Transporter MDR1 to Potentiate Antifungal Activity
(Georgetown University, 2013)Fungal invasive infections of humans are now called "hidden killers". The rising costs of treatment are associated with inappropriate therapy, defined as delayed intervention, inadequate dosage, or administration of an ... -
Hippocampal Microcircuit Alterations in Early Amyloid Pathology: A Selective Impairment of Parvalbumin-Expressing Basket Cells During Sharp Wave Ripple Events
(Georgetown University, 2020)Memory disruption in mild cognitive impairment (MCI) and Alzheimer’s disease (AD) is poorly understood, particularly at early stages preceding neurodegeneration. In mouse models of AD, there are disruptions to sharp wave ... -
Histone ADP-ribosylation by Poly(ADP-ribose) Polymerase 1 (PARP1) Facilitates Inflammatory Gene Transcription by Directly Altering Nucleosome Structure
(Georgetown University, 2012)The packaging of DNA into nucleosomes imposes obstacles to gene transcription as they limit the accessibility of DNA to the transcription machinery. As such, the modulation of nucleosome structure by histone-modifying and ... -
HIV-induced Matrix Metalloproteinases Alter Llial and Neuronal Function
(Georgetown University, 2019)Approximately 37 million individuals are currently infected with human immunodeficiency virus (HIV). The advent of combination antiretroviral therapy (cART) has revolutionized the treatment of HIV by dramatically increasing ... -
Homeostatic control of AMPA receptor strength and subunit composition by Polo-like kinase 2
(Georgetown University, 2009) -
Human APOE4 Affects Microglial Reactivity and Spatial Cognition in a Mouse Model of Alzheimer's Disease Risk
(Georgetown University, 2015)Alzheimer's disease (AD) is a progressive age-related neurodegenerative disorder that results in declarative memory deficits. Apolipoprotein e4 (APOE-ε4) is the strongest genetic risk factor for developing AD, and influences ... -
The Human Papillomavirus Type 16 E5 Protein: Stress Signaling and Expression in Cervical Cancer Cell Lines
(Georgetown University, 2012)ABSTRACT -
Hypo-Pigmented Burn Hypertrophic Scar Contains Melanocytes that Can Be Signaled to Re-pigment by Alpha Melanocyte Stimulating Hormone
(Georgetown University, 2020)Despite good acute burn management, hypertrophic scars (HTSs) can develop, and has been reported in 70% of healed burns. An understudied symptom of HTS is the dyschromia of the epidermal cells, and no current treatments ... -
Hyponatremia is Associated with Increased Osteoporosis and Bone Fractures in Diabetics with Matched Glycemic Control: Supplemental Materials
(2018-12-04)Purpose Patients with diabetes mellitus are at increased risk for bone fragility fracture secondary to multiple mechanisms. Hyperglycemia can induce true dilutional hyponatremia. Hyponatremia is associated with gait ...
