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Hippocampal Microcircuit Alterations in Early Amyloid Pathology: A Selective Impairment of Parvalbumin-Expressing Basket Cells During Sharp Wave Ripple Events
(Georgetown University, 2020)
Memory disruption in mild cognitive impairment (MCI) and Alzheimer’s disease (AD) is poorly understood, particularly at early stages preceding neurodegeneration. In mouse models of AD, there are disruptions to sharp wave ...