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  Characterization and Phase Transformation of Biogenic and Synthetic Uric Acid Forms 

  Thornton, Alyssa (Georgetown University, 2023)

  Though the major nitrogen waste form in humans is urea, any uric acid that is produced from purine metabolism cannot be further oxidized due to the silencing of the uricase enzyme. Uric acid crystallization is associated ...
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  Understanding Dynamics and Structural Properties of Osmolytes and Water 

  Liu, Bailang (Georgetown University, 2023)

  Organic cosolutes can have profound effects on protein stability, and the molecular origins of these differences can be elucidated by examining their behavior in aqueous solutions. While urea and methyl-substituted urea ...
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  Cycloalkyl Strapped Monomers for the Controlled Synthesis of Higher Dimensional π-Conjugated Materials 

  Mohanan, Manikandan (Georgetown University, 2023)

  Higher dimensional π-conjugated polymers are desirable for sensing, storage, separation, energy, and optoelectronic applications. Nevertheless, it is challenging to control the higher dimensional polymer growth and fine ...
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  I. Synthesis, Characterization, and Properties of Low Molecular Mass Fatty Acid Gelators II. Poly(Dimethylsiloxane)s Functionalized with Thiols and Disulfides 

  Beaupre, Danielle Marie (Georgetown University, 2013)

  This dissertation describes two research projects, both of which involve compounds that contain thiol (RSH) and/or disulfide (RSSR) groups. Often, thiols and disulfides can be interconverted with relative ease. First, this ...
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  Exploring Allostery in the cAMP-Receptor Protein from Mycobacterium Tuberculosis through Structural and Thermodynamic Amino Acid Substitutions 

  Dokas, Stephen Peter (Georgetown University, 2023)

  The bacterial transcription factor cAMP receptor protein (CRP) plays a vital role in gene expression by facilitating RNA polymerase binding at specific promoter sites. Understanding the allosteric regulation of CRP from ...

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