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Cover for The Molecular Determinants of Tumor Cell Sensitivity and Resistance to Antibody-Dependent Cellular Cytotoxicity (ADCC)

The Molecular Determinants of Tumor Cell Sensitivity and Resistance to Antibody-Dependent Cellular Cytotoxicity (ADCC)

Murray, Joseph Christopher (Georgetown University, 2013)

Monoclonal antibodies represent the vanguard of targeted therapy due to their specificity and versatility. Aside from disrupting tumor cell survival and proliferation through cell surface receptor interactions, antibodies ...

Cover for Induction of apoptosis and autophagy by the small molecule inhibitor VMY-1-103 in cancer cell lines and reduction of tumor growth in vivo

Induction of apoptosis and autophagy by the small molecule inhibitor VMY-1-103 in cancer cell lines and reduction of tumor growth in vivo

Sirajuddin, Paul (Georgetown University, 2013)

Cancer is a class of diseases in which cells divide uncontrollably and are able to spread throughout the body. In particular, cancer of the prostate and brain, specifically medulloblastoma, are particularly deadly because ...