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  Modulation of Synaptic Plasticity by Phosphorylation of Amyloid Precursor Protein at Distinct Residues 

  Garcia DuBar, Selena Nicole (Georgetown University, 2023)

  Alzheimer's Disease (AD), the most common neurodegenerative disorder, is characterized by progressive cognitive impairment. Histopathological hallmarks include Aβ accumulation and tau phosphorylation. Aβ formation starts ...
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  Deficiency in CCR5, a Mediator of Neuroinflammation, Normalizes TIMP Levels, Working Memory, and Gamma Oscillation Power in APOE4 Targeted Replacement Mice 

  Greco, Griffin Alexander (Georgetown University, 2023)

  The APOE4 allele increases the risk for Alzheimer’s disease (AD) in a dose-dependent manner and is also associated with cognitive decline in non-demented elderly controls. In mice with targeted gene replacement (TR) of ...
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  Cochlear Hair Cell Innervation Is Dependent on a Modulatory Function of Semaphorin-3A 

  Cantu, Homero Lael (Georgetown University, 2023)

  Proper connectivity between type I spiral ganglion neurons (SGNs) and inner hair cells (IHCs) in the cochlea is necessary for conveying sound information to the brain in mammals. Previous studies have shown that type I ...
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  Matrix Metalloproteinase-9 Inhibition Modulates Sharp Wave Events and Memory Consolidation in Juvenile but not Adult Zebrafish 

  Blanco, Ismary (Georgetown University, 2023)

  Hippocampal-dependent learning and memory deficits are a hallmark of many neurological disorders resulting from the dysregulation in the circuitry that gives rise to sharp wave ripple (SWR) events, the neural correlates ...
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  Brain Anatomy in Bilingual Children and Its Relationship to Reading Ability 

  Schug, Alison Kay (Georgetown University, 2023)

  Gray matter volume (GMV) differences have been documented in early bilingual adults relative to monolingual adults and separately in children and adults with the reading disability (RD) developmental dyslexia. It is not ...

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