Search

Now showing items 1-2 of 2

Cover for Regulation of Angiotensin Type 1 Receptor Function by an Upstream Short Open Reading Frame (sORF) in the mRNA 5' Leader Sequence

Regulation of Angiotensin Type 1 Receptor Function by an Upstream Short Open Reading Frame (sORF) in the mRNA 5' Leader Sequence

Kadam, Parnika Sandesh (Georgetown University, 2019)

The angiotensin type 1 receptor (AT1R) plays a critical role in blood pressure control. In this study, we investigated the role of an upstream short open reading frame (sORF) in AT1aR signaling. We investigated Angiotensin ...

Cover for Identifying and Evaluating Mechanisms of Drug Resistance in Cancer

Identifying and Evaluating Mechanisms of Drug Resistance in Cancer

Martin, Kelly A (Georgetown University, 2019)

Bladder cancer is among the top ten most common cancers, with about ~380,000 new cases and ~150,000 deaths per year worldwide. We have utilized a patient-derived bladder cancer xenograft (PDX) platform to characterize ...