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The Role of T Cells in the Hypertension of the Female Dahl Salt-Sensitive Rat
(Georgetown University, 2018)
Hypertension (HT) is a major risk factor for cardiovascular diseases (CVD) and affects 1 billion men and women globally. The underlying cause of HT in women is far less studied than in men. Hence it is critically important ...
The Application of Conditional Reprogramming to Drug Discovery and Regenerative Medicine
(Georgetown University, 2018)
The Conditional Reprogramming (CR) method has been shown to induce an in vitro stem-like state allowing for the continuous growth of patient-derived epithelial cells. Due to this new culture system, it has been possible ...
RARRES1 Modulation of Tubulin Deglutamylation Regulates Metabolism and Cell Survival
(Georgetown University, 2018)
One of the driving mechanisms of cancer progression is the reprogramming of metabolic pathways in intermediary metabolism. Cancers increase their energy expenditure by increasing ATP production for utilization in anabolic ...