Speech and music production require repeated and accurate coordination between actions and sounds. This tightly regulated set of audiomotor interactions seems to persist for receptive speech and music perception as well. ...

Alzheimer's disease (AD), unlike the other leading causes of death, does not have a cure or an effective intervention strategy. The largest genetic risk factor for AD is APOE, with the ε4 allele increasing and the ε2 allele ...

Working memory is involved in numerous areas of cognition. It has been studied using various tasks, in which cognitive performance and brain activation have been measured. Working memory depends largely on dopamine ...

Executive control, the goal directed deployment of cognitive resources, depends critically on a class of neurotransmitters called catecholamines. One such catecholamine, norepinephrine, is theorized to facilitate cognition ...

PTSD can develop following exposure to a traumatic event or events resulting in symptoms of hyperarousal, avoidance and the re-experiencing of events related to the trauma experience. Sleep disturbance may contribute to ...

Aphasia is an acquired impairment of language typically caused by stroke, and almost always includes anomia, difficulty with naming and word finding. Anecdotally, people with aphasia often report being able to say internally ...

Here we investigated whether traumatic brain injury (TBI) altered the regulation of cholesterol 24S-hydroxylase (Cyp46), an enzyme that converts cholesterol to the more hydrophilic 24S-hydroxycholesterol. We examined changes ...

The mammalian cerebral cortex begins to take shape during embryonic development. The generation of cortical neurons is stereotyped: initial proliferation of cells is followed by differentiation of progeny into neurons and ...

A hallmark of human cognition is the ability to rapidly assign meaning to sensory stimuli. In the domain of vision, it is generally thought that this fast object categorization ability is accomplished by a cortical ...

Written language is relatively new from an evolutionary standpoint; however, reading has become an essential aspect of success in everyday life. As with other acquired skills, the ability to learn to read is variable ...