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IL-27 Induces IFM/STAT1-Dependent Genes and Enhances Function of TIGIT+ HIVgag-Specific T Cells
(Georgetown University, 2022)
HIV-specific T cells have diminished effector function and fail to control/eliminate the virus. IL-27, a member of the IL-6/IL-12 cytokine superfamily has been shown to inhibit HIV replication. However, whether or not IL-27 ...