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Interactions with Innate Immunity Determine the Immunogenicity of Adenovirus Vectors Types 5, 28, and 35: Implications for Vaccine Design
(Georgetown University, 2012)
Recombinant adenovirus vectors (rAd) have proven to be very effective at inducing antigen-specific, polyfunctional T cell responses. Recombinant adenovirus serotype 5 (rAd5)-based vectors have been extensively studied as ...
Cell Subsets and Pathogen Recognition Requirements Involved in the Innate Response of Primary Human Monocytes and Dendritic Cells to Toxoplasma gondii
(Georgetown University, 2015)
As a major natural host for Toxoplasma gondii, the mouse is widely used for the study of the immune response to this medically important protozoan parasite. However, murine innate recognition of toxoplasma depends on the ...