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Cover for Probing The Flavivirus Life Cycle: Repurposing Amodiaquine as an Inhibitor of Flavivirus Infectivity and Functional Analysis of Flaviviral NS5 in 5'Capping

Probing The Flavivirus Life Cycle: Repurposing Amodiaquine as an Inhibitor of Flavivirus Infectivity and Functional Analysis of Flaviviral NS5 in 5'Capping

Boonyasuppayakorn, Siwaporn (Georgetown University, 2013)

Dengue virus serotypes 1-4 (DENV1-4) are transmitted by mosquitoes and are the most frequent cause of arboviral infections in the world. Neither vaccine nor antiviral drug is currently available. In this study, we discovered ...

Cover for Hijacking the Candida albicans Multidrug Resistant Transporter MDR1 to Potentiate Antifungal Activity

Hijacking the Candida albicans Multidrug Resistant Transporter MDR1 to Potentiate Antifungal Activity

Sun, Nuo (Georgetown University, 2013)

Fungal invasive infections of humans are now called "hidden killers". The rising costs of treatment are associated with inappropriate therapy, defined as delayed intervention, inadequate dosage, or administration of an ...