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Development of a Novel Transfection System to Study Regulation of Hepatitis Delta Virus RNAs by Hepatitis Delta Antigen
(Georgetown University, 2019)
Hepatitis delta virus (HDV) is a unique pathogen that co-infects with hepatitis B virus and increase the severity of acute and chronic liver disease. HDV is a negative stranded RNA virus and produces three processed RNAs ...
Regulation of the Complement System by Toxoplasma gondii Surface Coat Proteins SRS25, SRS29C, and SRS57
(Georgetown University, 2019)
Very little is known about how the protozoan parasite Toxoplasma gondii overcomes the complement system to establish infection. In this dissertation, I found significant differences in C3b deposition between T. gondii Type ...
Building Reslience to Biothreats: An Assessment of Unmet Core Global Health Security Needs
(EcoHealth Alliance, 2019)
Global health security is the bulwark against catastrophic public health events. Building this security is a timely and urgent challenge for the world as it faces an increasing rate of emergent and re-emergent infectious ...