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A Risk Assessment and Seir Model of Rift Valley Fever Virus in the State of Florida
(Georgetown University, 2014)
Rift Valley fever (RVF) is a mosquito-borne disease of medical and agricultural importance, affecting humans and ungulates in a disease spectrum stretching from mild, self limited illness to serious disease, abortion and ...
Examining the Role of STATs and STAT Signaling the Induction, Enhancement, and Prolonged Duration of Antiviral Activity by IFN-γ and IFN-α2a in Combination with Ribavirin
(Georgetown University, 2014)
Interferons (IFNs) were discovered in 1957, yet there are still questions as to how IFNs elicit their antiviral, antiproliferative, and immunomodulatory activities. In addition, IFN-α is part of the standard treatment ...
The Role of Affinity and Mechanism of Virus Attachment to Cells in Antibody-Dependent Enhancement and Neutralization of Flaviviruses
(Georgetown University, 2014)
Flaviviruses are RNA viruses that cause significant morbidity and mortality worldwide. There are currently no specific therapeutics or clinically licensed vaccines available for a number of flaviviruses, including dengue ...