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Cover for SIV-Specific CD8+ T Cells are Phenotypically, Functionally, and Clonotypically Distinct Across Lymphoid and Mucosal Tissues

SIV-Specific CD8+ T Cells are Phenotypically, Functionally, and Clonotypically Distinct Across Lymphoid and Mucosal Tissues

Starke, Carly Elizabeth Camille (Georgetown University, 2019)

CD8+ T cell responses are necessary for immune control of simian immunodeficiency virus (SIV). However, the key parameters that confer antiviral potency remain elusive, feasibly because most studies to date have been ...

Cover for Regulation of the Complement System by Toxoplasma gondii Surface Coat Proteins SRS25, SRS29C, and SRS57

Regulation of the Complement System by Toxoplasma gondii Surface Coat Proteins SRS25, SRS29C, and SRS57

Sikorski, Patricia Magdalena (Georgetown University, 2019)

Very little is known about how the protozoan parasite Toxoplasma gondii overcomes the complement system to establish infection. In this dissertation, I found significant differences in C3b deposition between T. gondii Type ...