The Ethics of the Randomized Clinical Trial
New England Journal of Medicine. 1982 Sep 16; 307(12): 719-724.
The physician who enlists a patient in a randomized clinical trial faces a potential conflict between his obligations to the patient and his commitment to promote scientific knowledge. Ethical dilemmas are analyzed as they arise from the need to sacrifice individualized treatment and to withhold information about the physician's intuitive treatment preferences. It is held to be unethical to solicit consent from a prospective subject without informing him that his treatment will be randomly selected. (KIE abstract)
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