Show simple item record

dc.creatorMarquis, Donen
dc.date.accessioned2015-05-05T18:13:29Zen
dc.date.available2015-05-05T18:13:29Zen
dc.date.created1983-08en
dc.date.issued1983-08en
dc.identifier10.2307/3561721en
dc.identifier.bibliographicCitationHastings Center Report. 1983 Aug; 13(4): 40-47.en
dc.identifier.issn0093-0334en
dc.identifier.urihttp://worldcatlibraries.org/registry/gateway?version=1.0&url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&atitle=Leaving+Therapy+to+Chance&title=Hastings+Center+Report.+&volume=13&issue=4&pages=40-47&date=1983&au=Marquis,+Donen
dc.identifier.urihttp://dx.doi.org/10.2307/3561721en
dc.identifier.urihttp://hdl.handle.net/10822/724293en
dc.description.abstractMarquis analyzes the design of randomized clinical trials of anticancer drugs and concludes that randomization is incompatible with the ethical obligations of the physician patient relationship. Statistical requirements and administrative complexities make it difficult to halt a trial before it has run its course, yet it is unethical to continue once there is evidence that one therapy is superior to another. Strategies for resolving the dilemma are proposed, but are shown to be ethically flawed upon closer examination. There appears to be no solution to the problem of reconciling the demonstrable benefits of randomized trials with inevitable violations of the therapeutic obligation. (KIE abstract)en
dc.formatArticleen
dc.languageenen
dc.sourceBRL:KIE/15550en
dc.subjectCanceren
dc.subjectClinical Trialsen
dc.subjectConsenten
dc.subjectDecision Makingen
dc.subjectDisclosureen
dc.subjectDrugsen
dc.subjectEthical Analysisen
dc.subjectHuman Experimentationen
dc.subjectInformed Consenten
dc.subjectInvestigatorsen
dc.subjectJusticeen
dc.subjectPatientsen
dc.subjectPhysician Patient Relationshipen
dc.subjectPhysiciansen
dc.subjectResearchen
dc.subjectResearch Designen
dc.subjectRisks and Benefitsen
dc.subjectSelection of Subjectsen
dc.subjectStatisticsen
dc.subjectTherapeutic Researchen
dc.subjectUtilitarianismen
dc.titleLeaving Therapy to Chanceen
dc.provenanceDigital citation created by the National Reference Center for Bioethics Literature at Georgetown University for the BIOETHICSLINE database, part of the Kennedy Institute of Ethics' Bioethics Information Retrieval Project funded by the United States National Library of Medicine.en
dc.provenanceDigital citation migrated from OpenText LiveLink Discovery Server database named NBIO hosted by the Bioethics Research Library to the DSpace collection BioethicsLine hosted by Georgetown University.en


This item appears in the following Collection(s)

Show simple item record


Georgetown University Seal
©2009—2022 Bioethics Research Library
Box 571212 Washington DC 20057-1212
202.687.3885