Progress Toward a More Ethical Method for Clinical Trials
Kadane, Joseph B.
Journal of Medicine and Philosophy. 1986 Nov; 11(4): 385-404.
Kadane explores the possibilities of using new methods of conducting clinical trials which assign patients to a treatment that at least one expert judges best for that patient. Bayesian methods are used for eliciting the opinions of medical experts which can be changed as information on treatments is collected. The author believes that, while most patients in clinical trials receive reasonable care, they may not receive the best possible care, and that alternatives to standard randomization techniques must be devised. He describes experience with a trial at Johns Hopkins using the optimal treatment method. (KIE abstract)
Alternatives; Clinical Trials; Competence; Control Groups; Consent; Decision Making; Disclosure; Evaluation; Human Experimentation; Informed Consent; Methods; Patients; Physician Patient Relationship; Politics; Professional Competence; Random Selection; Research; Research Design; Research Subjects; Risks and Benefits; Selection of Subjects; Statistics; Therapeutic Research;
Showing items related by title, author, creator and subject.